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81.
A model of single-species growth in the chemostat on two non-reproducing, growth-limiting, noninhibitory, perfectly substitutable resources is considered. The medium in the growth vessel is enriched by increasing the input concentration of one of the resources. Analytical methods are used to determine the effects of enrichment on the asymptotic behaviour of the model for different dilution rates. It is shown that there exists a threshold value for the dilution rate which depends on the maximal growth rate of the species on each of the resources. Provided the dilution rate is below the threshold, enrichment is beneficial in the sense that the carrying capacity of the environment is increased, regardless of which resource is used to enrich the environment. When the dilution rate is increased beyond the threshold, it becomes important to consider which resource is used for enrichment. For one of the resources it is shown that, while moderate enrichment can be beneficial, sufficient enrichment leads to the extinction of the microbial population. For the other resource, enrichment leads from washout or initial condition dependent outcomes to survival, and is thus beneficial. There are important implications of these results to the management of natural aquatic ecosystems. For example, while enrichment may be beneficial to the microbial species during the summer months, it can lead to their decimation during spring run-off, when the natural dilution rate is higher.Research partially supported by an Ontario Graduate Scholarship. This author's contribution was motivated by results in her Ph.D. thesis at McMaster UniversityResearch supported by the National Sciences and Engineering Research Council of Canada. 相似文献
82.
Kenneth P. Severin JoLynn Carroll Brenda L. Norcross 《Environmental Biology of Fishes》1995,43(3):269-283
Synopsis The incorporation of dissolved oceanic constituents in the otoliths of fish has potential as a chemical tracer for reconstructing the early life history of marine fish. Wavelength dispersive spectrometers on an electron microprobe were used to measure Na, Mg, P, S, Cl, K, Ca, and Sr concentrations on the outer margins of 57 juvenile walleye pollock, Theragra chalcogramma, otoliths from five locations in the Gulf of Alaska and Bering Sea. Discriminant analyses that used various combinations of Na, P, K, Sr, and fish standard length and/or age showed that 60–80% of the samples could be assigned to the correct capture locality. While the concentrations of some of the measured elements correlated with standard length or age of the fish, there are measurable differences among localities when concentrations are length or age corrected, mainly due to differences in Na and K concentrations. Elemental composition of otoliths potentially could be used to assign fish from a mixed stock fishery to original stocks, information that is greatly needed for the effective management of fish stocks. 相似文献
83.
Meningococcal pilin: a glycoprotein substituted with digalactosyl 2,4-diacetamido-2,4,6-trideoxyhexose 总被引:19,自引:8,他引:11
Elaine Stimson Mumtaz Virji Katherine Makepeace Anne Dell Howard R. Morris Gail Payne Jon R. Saunders Michael P. Jennings Stephanie Barker Maria Panico Ian Blench E. Richard Moxon 《Molecular microbiology》1995,17(6):1201-1214
Neisseria meningitidis pili are filamentous protein structures that are essential adhesins in capsulate bacteria. Pili of adhesion variants of meningococcal strain C311 contain glycosyl residues on pilin (PilE), their major structural subunit. Despite the presence of three potential N -linked glycosylation sites, none appears to be occupied in these pilins. Instead, a novel O -linked trisaccharide substituent, not previously found as a constituent of glycoproteins, is present within a peptide spanning amino acid residues 45 to 73 of the PilE molecule. This structure contains a terminal 1-4-linked digalactose moiety covalently linked to a 2,4-diacetamido-2,4,6-trideoxyhexose sugar which is directly attached to pilin. Pilins derived from galactose epimerase ( galE ) mutants lack the digalactosyl moiety, but retain the diacetamidotrideoxyhexose substitution. Both parental (#3) pilins and those derived from a hyper-adherent variant (#16) contained identical sugar substitutions in this region of pilin, and galE mutants of #3 were similar to the parental phenotype in their adherence to host cells. These studies have confirmed our previous observations that meningococcal pili are glycosylated and provided the first structural evidence for the presence of covalently linked carbohydrate on pili. In addition, they have revealed a completely novel protein/saccharide linkage. 相似文献
84.
85.
Brenda J. Claiborne Allen I. Selverston 《Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology》1984,154(1):27-32
Summary The cell bodies of the inferior ventricular nerve (IVN) through-fibers of the lobster stomatogastric nervous system were located using cobalt chloride backfills and intracellular recordings. Following backfills of the IVN, two cell bodies in the supraesophageal ganglion (or brain) were stained with cobalt. These cells, each approximately 30 m in diameter, were located at the base of the IVN, just inside the connective tissue sheath surrounding the brain, and were identifiable on the basis of their close proximity to the IVN.In order to record from the cells, an in vitro preparation was made which included the cell bodies, their axons in the IVN and the stomatogastric nervous system. Intracellular recordings showed that the axons projected to the stomatogastric ganglion and made synaptic connections onto identified neurons. The axon trajectories and synaptic connections correlated with those previously described for the IVN through-fibers using extracellular stimulation and recording techniques.Abbreviations
IVN
inferior ventricular nerve
-
SN
stomatogastric nerve 相似文献
86.
Summary We examined metaphases from three patients with chronic myeloid leukaemia and a typical Philadelphia chromosome with one chromosome 9 as the recipient to determine whether the 9q+ 22q- translocation is reciprocal. Good quality G-banded photographs of the chromosomes concerned were subjected to light absorption density analysis. This provided enlarged tracings corresponding to the relevant chromosome regions and so facilitated accurate measurement. This technique has unambiguously shown that the typical Philadelphia chromosome results from a reciprocal translocation and that probably no material is gained or lost in the exchange. Furthermore, in a total of six patients for whom sequential G and C banding was performed, the chromosome 9 with the largest block of centromeric heterochromatin received the translocated material. We offer tentative explanations for this curious observation. 相似文献
87.
R N Bergman 《Federation proceedings》1977,36(2):265-270
The rates of storage and release of carbohydrate by the liver are determined by the plasma concentrations of several blood-borne signals; most important are the concentrations of glucose, and of the hormones insulin and glucagon. To understand the complex control relationships of these three signals as they affect the liver, their individual dynamic influences have been determined experimentally, and the findings have been integrated by means of a computer simulation of the pathways of hepatic glycogen metabolism. The simulation studies have led to specific hypotheses about the biochemical effects of glucose and insulin on the liver. The simulation studies have also led to the conclusion that glucose exerts a rapid moment-to-moment influence on the rate of uptake of glucose by the liver. Insulin, however, by exerting a slower influence on the sensitivity of the liver to glucose, is very effective in "optimizing" the amount of glycogen which the liver stores during food intake. Thus, integrated experimental and simulation studies can lead to a view of a physiological regulating system which does not emerge from either approach used alone.- 相似文献
88.
The microsporidium Pleistophora crangoni n. sp. is a common parasite of Crangon franciscorum, C. nigricauda, and C. stylirostris in the vicinity of Yaquina Bay, Oregon. Characteristics of the parasite are described. Skeletal muscle was the only host tissue infected. The seasonal prevalence and intensity of the parasite in crangonids are described, based on examination of 1556 C. franciscorum, 3877 C. nigricauda, and 1674 C. stylirostris collected at monthly intervals from June 1975 through June 1976. Prevalence in C. franciscorum and C. stylirostris increased through the autumn and reached winter peaks of 30.3 and 41.0%, respectively, then decreased in the spring. Prevalence in C. nigricauda remained below 8% through the year. Intensity increased with size of the shrimps in the three species. Infection experiments and field observations suggest that only very young shrimps are susceptible to infection during a relatively short period during the summer months. Following natural infection, the parasite spreads within the host, indicating repeated schizogonic cycles. Parasitic castration was indicated by the absence of gravid infected female shrimps and was confirmed by histological examination. Ovaries of infected shrimps did not develop beyond a very early stage. A shift in sex ratio toward females in infected shrimps indicates that the parasite may influence sex determination. Shrimps showed little cellular response to infection. Only rarely in heavily infected shrimps was encapsulation of parasite cysts observed; necrotic tissue was occasionally observed. Infected shrimps usually succumbed before uninfected shrimps when subjected to oxygen stress. The collection of infected shrimps that were unusually large may indicate that these individuals grew faster or lived longer than uninfected shrimps. 相似文献
89.
Resistance to two cultured lines of murine embryonal carcinoma was studied in F1 hybrids constructed between the tumor-syngeneic mouse strain 129/J and several allogeneic strains. Three of four such hybrid strains were significantly more resistant to the multipotent embryonal carcinoma line PCC3 than the tumor-syngeneic 129/J parent strain. All hybrid strains tested showed significantly higher resistance to the nullipotent embryonal carcinoma line F9 than the syngeneic strain.Hybrid resistance to embryonal carcinoma lines does not require a hybridH-2 complex.Several kinds of evidence indicate that this hybrid resistance has an immunological basis. 相似文献
90.
South-Central European fossil hominids dated to the Upper Pleistocene exhibit a distinct morphological and metric continuum in supraorbital form from early Neandertal (Krapina), through late Neandertals (Vindija), to early Upper Paleolithic hominids. The supraorbital morphologies pertinent to this continuum are documented, and the alterations in size and morphology are discussed ralative to the function of supraorbital superstructures and their relationship to overall craniofacial form. It is concluded that this continuum most likely reflects localized transition between Neandertals and modern man in this region of Europe. 相似文献